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essential thrombocythaemia : ウィキペディア英語版 | essential thrombocythaemia
Essential thrombocythaemia (ET; also known as essential thrombocytosis, essential thrombocythemia, primary thrombocytosis) is a rare chronic blood disorder characterised by the overproduction of platelets by megakaryocytes in the bone marrow.〔 It may, albeit rarely, develop into acute myeloid leukaemia or myelofibrosis.〔 It is one of four myeloproliferative disorders (disorders characterised by increased production of a particular line of blood cell). ==Signs and symptoms== Most people with ET are without symptoms referable to ET at the time of diagnosis, which is usually ultimately made after noting an elevated platelet level on a routine complete blood count (CBC). The most common symptoms are bleeding, blood clots, headache, nausea, vomiting, abdominal pain, visual disturbances, dizziness, fainting, and numbness in the extremities; the most common signs are increased white blood cell count, reduced red blood cell count, and enlarged spleen.〔
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